Targeting the ACOD1-itaconate axis stabilizes atherosclerotic plaques.

Statistical significance is displayed as ∗ p < 0.05, ∗∗ p < 0.01 and ∗∗∗ p < 0.001 whilst a statistical trend of p < 0.1 and >0.05 is displayed as a number.

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Fractional contribution of different triglyceride (TG) isotope species showed a trend of TG's with shorter long chain fatty acids (LCFA's) comprising of 40–49 total carbons ( Fig. 5 B) contained more M+3 labelling in Acod1 −/− BMDMs which was not observed for TG's with longer LCFA's containing 50–62 total carbons ( Fig. 5 C & Supp.

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