IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling.

Gene Ontology analysis of the upregulated genes (log2fold change≥1, padj<0.05) revealed that most of the biological processes induced by IFN-β in WT organoids were linked to a functional STAT2 given the fact that they did not reach statistical significance in Stat2 −/− organoids stimulated with IFN-β ( online supplemental figure 6B ; processes of bars marked in red in the second panel).

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