a clear trendp = 0.15
For the expression of ER-alpha, a significant result was also observed that the TFP group in reference samples was greater than the TFN group with a clear trend (one-sided Wilcoxon rank-sum, ESR1|ER-alpha, p = 0.15; ESR1|ER-alpha_pS118, p = 0.05, Fig. 3 C).