Lung metastases were identified in all mice, however, the metastatic load in lung, evaluated via bioluminescence imaging, showed a trend towards a dose-dependent reduction upon treatment, although not reaching statistical significance.
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GT-00AxIL15, a Novel Tumor-Targeted IL-15-Based Immunocytokine for the Treatment of TA-MUC1-Positive Solid Tumors: Preclinical In Vitro and In Vivo Pharmacodynamics and Biodistribution Studies.
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