Alterations in Plasma Lipid Profiles Associated with Melanoma and Therapy Resistance.

Higher plasma levels of FASN were observed in LR patients ( Figure 1 E) with a borderline significance (OR: 1.571; 95%CI: 0.976; 2.528), whereas no association was observed between DHCR24 and treatment response ( Figure 1 F) and with the other considered plasma variables ( Table S1 ).

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Notably, with respect to SR, LR patients showed a trend for higher levels of DHCer, Cer, SM, and LacCer, while the levels of GM3 revealed an opposite trend with higher values in SR.

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