Neovascular age-related macular degeneration: disease pathogenesis and current state of molecular biomarkers predicting treatment response-a scoping review.

61 A trend for a higher probability of not responding to treatment has been observed for variants rs699947 CC, rs833061 TT and rs1570360 GG, although these results did not reach statistical significance. 62 For VEGFA rs3025039, the TT genotype was associated with a higher probability of improvement of visual acuity by ≥15 letters in a prospective, Korean study of newly diagnosed wet patients with AMD treated with ranibizumab with a loading phase followed by PRN. 63 In another study, ranibizumab tr

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