Comparative pharmacokinetics of polymyxin B in critically ill elderly patients with extensively drug-resistant gram-negative bacteria infections.

found that the mean AUC ss, 24 h of PMB in their renal insufficiency group was higher than in their normal renal function group, with marginal significance ( Wang et al., 2021a ).

also in 5,069 other papers

Statistical significance was set at p < 0.05, and highly significant values had a significance of p < 0.01. 3 Results 3.1 Characteristics of patients at enrollment and clinical infection A total of 23 critically ill patients who received PMB for XDR-GNB infections were enrolled in this study, of whom 17 were elderly patients and the other 6 were young patients.

also in 132,142 other papers

The patients with AUC ss, 0–24 h more than 100 mg·h/L were older than patients with AUC ss, 0–24 h less than 50 mg·h/L ( p = 0.059) and had lower CrCl than patients with AUC ss, 0–24 h ranging from 50 to 100 mg·h/L ( p = 0.061) ( Figure 2 ), but the p values did not reach statistical significance.

also in 111,027 other papers