Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach.

BLI signal at endpoint showed a trend of being inversely correlated with time to endpoint ( Table 3 ; Fig. 6A and B ) demonstrating that higher metastatic burden causes increased morbidity in vivo .

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