Evaluation of single-use optical and electrochemical pH sensors in upstream bioprocessing.

Although there is statistical significance between 400 and 500 and > 500 mOsm/kg, the lack of a clear trend of increasing inaccuracy aligning with increased osmolality does not allow us to conclude any relationship between osmolality and SU OPT accuracy from our data sets. 3.7.

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The patterns are very similar for overall relative glycosylation, sialyation, and high mannose species, with a slight trend of reduced fucosylation at the pH 7.3 condition (59.10% ± 2.34% versus 64.40% ± 3.75%).

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2 B), there was an interesting trend of increasing accuracy with increasing pH that is not apparent for the other pH sensor types.

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