Contractility defects hinder glycoprotein VI-mediated platelet activation and affect platelet functions beyond clot contraction.

High-dose (40 μM) BBT caused a significant reduction of the adhesion rate and resulted in tendentially less platelet interactions with the surface, but faster rolling and shorter distance traveled; however, these did not reach statistical significance due to the relatively large variability between individual experiments ( Supplementary Figure S4 ).

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