Novel anti-neuroinflammatory pyranone-carbamate derivatives as selective butyrylcholinesterase inhibitors for treating Alzheimer's disease.

J Enzyme Inhib Med Chem · 2024 · PMC10878344 · PMID 38362862

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showed a trendno p-value reported

In addition to the eqBuChE assay, we confirmed the inhibitory efficacy of compounds 7a–7k by the huBuChE assay ( Table 1 ), and summarised their structure-activity relationships (SAR), which showed a trend similar to that of the eqBuChE assay.

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