Salivary and serum nitric oxide synthase, macrophage inflammatory protein 1 alpha and macrophage migration inhibitory factor levels in periodontal disease.

Although slight increase was observed in these levels in parallel with the severity of disease, differences did not reach statistical significance ( Table 5 , Fig. 2 ). 3.4 Highest MIF concentration in serum was observed in stage I–II periodontitis group Difference was not observed between gingivitis and periodontitis in terms of MIF concentrations in serum and saliva.

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