All of the P values were two-sided, P < 0.05/255 = 2.00E-4 for circulating metabolites and P < 0.05/18 = 2.80E-3 for urinary metabolites were considered to be statistically significant, and P < 0.05 but that which did not reach statistical significance was considered suggestively significant.
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Causal relationships of metabolites with allergic diseases: a trans-ethnic Mendelian randomization study.
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The sentences
Recent epidemiological studies have shown an increasing trend in the prevalence of allergic diseases, with approximately 22% of residents in 30 countries affected [ 4 ].