Barely Significant
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Microglial knockdown does not affect acute withdrawal but delays analgesic tolerance from oxycodone in male and female C57BL/6J mice.

Adv Drug Alcohol Res · 2022 · PMC10880796 · PMID 38390615

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approached significanceno p-value reported
Of note, the Treatment X Sex interaction approached significance and was comprised of Oxy and PLX+Oxy female groups exhibiting ∼1°C greater decrease in body temperature compared to males.

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