A similar trend of MYCN mRNA reduction was also observed on transfection of dCas9 targeting MYCN-binding site; however, it did not reach statistical significance ( Figure S5 ).
← all excerpts
Inhibition of OCT4 binding at the <i>MYCN</i> locus induces neuroblastoma cell death accompanied by downregulation of transcripts with high-open reading frame dominance.
1
—
—