Moreover, supernatants collected from day 3 superantigen stimulated cells from the 2 donors showed a trend for lower IFN-γ content after hypoxic GBM-derived EV exposure, although this did not always reach statistical significance (data not shown).
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Hypoxic glioblastoma-cell-derived extracellular vesicles impair cGAS-STING activity in macrophages.
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