Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of <i>Brucella abortus</i> infection.

Front Immunol · 2024 · PMC10885698 · PMID 38404575

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did not reach statistical significancep=0.06so close (0.05 < p ≤ 0.1)

Moreover, reduced LDH release was also found in GBP2/5 double silenced BMDMs, although it did not reach statistical significance (p=0.06 comparing siGBP2/5 versus siCTL; Supplementary Figure 2 ).

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