Low nuclear expression of HIF-hydroxylases PHD2/EGLN1 and PHD3/EGLN3 are associated with poor recurrence-free survival in clear cell renal cell carcinoma.

Cancer Med · 2024 · PMC10891444 · PMID 38400673

Europe PMC DOI

hedged sentence

0.9200

closest p · 18.4× alpha

0.9200

boldest claim

The sentences

did not reach statistical significancep = 0.920not close (p > 0.1)

Cytoplasmic expressions of both HIF‐1α and HIF‐2α were significantly associated with shorter RFS in the Helsinki training cohort (log‐rank p = 0.004 and p < 0.001) but did not reach statistical significance in the Turku validation cohort (log‐rank p = 0.920 and p = 0.784).

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