Collaborative Metabolism: Gut Microbes Play a Key Role in Canine and Feline Bile Acid Metabolism.

Although it did not reach statistical significance, likely due to inter-dog variability, dogs receiving Tylosin at baseline had BA pools predominated by microbial-derived SBAs (93.9%) which precipitously dropped to 14.5% immediately after Tylosin, 10% at 2 weeks post antimicrobial administration, and only recovered to 22.9% eight weeks post antimicrobial administration [ 118 ].

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