HIV-1 Reverse Transcriptase Expression in HPV16-Infected Epidermoid Carcinoma Cells Alters E6 Expression and Cellular Metabolism, and Induces a Hybrid Epithelial/Mesenchymal Cell Phenotype.

In contrast to glycolysis, for these parameters, there was a negative association with E6*I expression as well which was highly significant ( p < 0.01), indicating that the inhibition of mitochondrial respiration was determined by both the levels of RT_A and the levels of E6*I .

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The expression of E6*I had a positive effect, but it did not reach statistical significance ( Table 3 ).

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