Osteocalcin of maternal and embryonic origins synergize to establish homeostasis in offspring.

In agreement with these results, glucose-stimulated insulin release was consistently hampered, albeit these differences did not reach statistical significance because of variability between samples, in Ocn GK +/− mice born from Ocn GK +/− or Ocn GK −/− mothers but not in those born from Ocn GK WT mice (Figs. 3A and EV2A ).

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