IL-6 predicts non-suicidal self-injury over 3 months in high-risk adolescents.

The associations between IL-6 and self-harm and between IL-6 and NSSI specifically remained statistically significant with the additional control of depression symptoms, SSRI use, age and past-month smoking. We also found a positive association between CRP and self-harm, but this relationship did not reach statistical significance (self-harm, B = 0.48, s.e. = 0.27, P = 0.089; NSSI, B = 0.56, s.e. = 0.28, P = 0.054); see Table 2 .

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