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Exploring the relationship between intestinal microbiota and immune checkpoint inhibitors in the treatment of non-small cell lung cancer: insights from the "lung and large intestine stand in exterior-interior relationship" theory.

Front Cell Infect Microbiol · 2024 · PMC10898591 · PMID 38415012

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did not reach statistical significancep > 0.05actually significant
Furthermore, PD-L1+ patients exhibited higher absolute counts of immune parameters for CD3 + and CD4 + T cells, but lower counts of CD8 + T cells than PD-L1- patients, although these differences did not reach statistical significance ( p > 0.05) ( Table 4 , Figures 12A–D ). 3.2.4 Effects of ICIs on the immune microenvironment of NSCLC patients with different TCM syndromes Patients diagnosed with advanced lung cancer predominantly exhibit Zheng-deficiency.

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