The updated interactomes, integrating the latest genetic findings of PD and SZ, recapitulated the groups of genes following the temporal profiles and disease affiliations of DGN2 and DGN3 with high significance and that of DGN1 with modest significance (Supplementary Note S 7 and Supplementary Fig.
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Parkinson's disease and schizophrenia interactomes contain temporally distinct gene clusters underlying comorbid mechanisms and unique disease processes.
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