(B) Normalized counts of IL8 and IL1A genes from RNAseq data in T47D WT spheroids (grey bars) or SAMHD1-KO spheroids (blue bars), confirming expression downregulation upon SAMHD1 depletion, although it did not reach statistical significance.
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SAMHD1 expression is a surrogate marker of immune infiltration and determines prognosis after neoadjuvant chemotherapy in early breast cancer.
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