Relationship between time-weighted average glucose and mortality in critically ill patients: a retrospective analysis of the MIMIC-IV database.

Compared with TWAG < 110 mg/dL plus − 15.1 < glycemic distance ≤ 20.1 mg/dL, TWAG 110–140 mg/dL plus glycemic distance ≤ − 15.1 mg/dL showed a lower risk of ICU mortality, while the difference did not reach statistical significance.

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The ORs showed an increasing trend with increased TWAG and glycemic distance; however, the risk of ICU mortality was significantly increased only with TWAG > 110 mg/dL at the same time as glycemic distance > 20.1 mg/dL ( p < 0.01).

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