A model of human neural networks reveals NPTX2 pathology in ALS and FTLD.

Nature · 2024 · PMC10901740 · PMID 38355792

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

Comparison of the TDP-43–HA-positive cell counts after treatment with the control shRNAs showed either no effect or a slight increase in toxicity, whereas treatment with one of the two NPTX2 shRNAs showed a mild benefit that did not reach statistical significance (Extended Data Fig. 13i ), possibly related to off-target toxicity that is often associated with shRNA treatment.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.