Association of tryptophan pathway metabolites with mortality and effectiveness of nutritional support among patients at nutritional risk: secondary analysis of a randomized clinical trial.

The nutritional support intervention showed a trend toward a beneficial effect and lower risk of 30-day mortality in patients with high tryptophan levels (adjusted HR 0.61 [95% CI 0.29–1.29, p 0.195]), but not in patients with low tryptophan levels (adjusted HR 1.72 [95% CI 0.79–3.70, p 0.169]) ( Figure 3 ).

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