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The FLRT3-UNC5B checkpoint pathway inhibits T cell-based cancer immunotherapies.

Sci Adv · 2024 · PMC10906930 · PMID 38427724

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In the EGFR/RD model, similar effects were observed on tumor growth and T cell recruitment but did not reach statistical significance ( Fig. 5D ), which may be attributed to different T cell mode activity that will require further studies.

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