Bispecific antibodies promote natural killer cell-mediated elimination of HIV-1 reservoir cells.

The HDAC inhibitor romidepsin elicited a significant increase in caRNA transcripts in one of two participants (designated as DEL-SPC-044), but the corresponding reductions in intact provirus + cells relative to the H2-Db control (11% with PG16-Db, 17% with 3BNC117-Db and 16% with PG16-Db + 3BNC117-Db) in this participant did not reach statistical significance (Fig. 4a ).

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