Riboflavin-LSD1 axis participates in the in vivo tumor-associated macrophage morphology in human colorectal liver metastases.

In agreement with the LSD1 upregulation, the M2 macrophages exposed to TNFα showed increased expression of SLC52A3 and SLC2A2 (although the latter did not reach statistical significance) compared to M2 macrophages cultured with TGFβ (Fig. 4 C).

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