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Immunohistochemical Evaluation of Perlecan (Heparan Sulphate Proteoglycan 2) Expression in Invasive Female Breast Carcinoma.

Asian Pac J Cancer Prev · 2023 · PMC10909087 · PMID 38156864

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In conclusion, although Perlecan immunohistochemical expression did not reach statistical significance with any of the studied parameters, we observed higher expression in cases with poor prognostic factors, including high grade, more advanced stage with nodal metastasis and LVI, as well as cases with Her2 neu overexpression and higher Ki-67 proliferation index.

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