Epigenome-wide association study of long-term psychosocial stress in older adults.

When assessing the relationship between the six individual stress domains and the nine CpG sites, we found that acute life events, financial stress, and lifetime discrimination domains had at least nominally significant associations with all CpG sites ( p < 0.05), while neighbourhood stress, relationship stress, and childhood adversity each had nominal associations with at least six CpG sites (Supplemental Table S5).

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