A randomized clinical trial with a weekly exenatide injection during 36 weeks in 42 patients between the age of 10–25 years with hypothalamic obesity mainly due to a craniopharyngioma did not show a significant difference in body weight change (−3.6 kg) but showed a clear trend for reduced fat mass in treated patients [ 29 ].
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Evaluating the effectiveness and underlying mechanisms of incretin-based treatments for hypothalamic obesity: A narrative review.
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