Midlife sensory and motor functions improve prediction of blood-based measures of neurodegeneration and Alzheimer's disease in late middle-age.

In sex‐stratified models, the magnitude of change in AUC for men and women was only statistically significant among men for the CAIDE model and showed a trend for improvements for the FRS% model (Table 2 ). 3.2 Ten‐year incidence of NfL positivity The AUC for prediction of incident NfL positivity using the CAIDE score and FRS% were 0.68 and 0.69, respectively.

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