The Potential of Twendee X^® as a Safe Antioxidant Treatment for Systemic Sclerosis.

Il-17 showed a decreasing trend compared to the PBS-treated mice (−6%), although the difference was not significant.

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In this study, HOCl-induced SSc mice showed a trend towards higher expression of Il-6 and Il-33 mRNA, but the change was not significant compared to PBS-treated mice (IL-6: +1%, IL-33: +1%).

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The expression of CD86 and Ly6C showed an increasing trend in macrophages of HOCl-induced SSc mice compared to controls (CD86: +3%, Ly6C: +3%, Not significant) ( Figure 6 B,D); in the expression of CD206, there was an increase compared to controls (+51% (Not significant)) ( Figure 6 C).

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