AAV-mediated hepatic expression of SLC30A10 and the Thr95Ile variant attenuates manganese excess and other phenotypes in Slc30a10-deficient mice.

We did assess bile flow rates during our bile collection surgeries and noted that bile flow rates were increased in mutant mice then decreased when mutant mice were treated with T95 or I95 AAV, although most changes did not reach statistical significance ( Fig. 4 F ).

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