A modified Mediterranean-style diet enhances brain function via specific gut-microbiome-brain mechanisms.

Although these differences did not reach a statistically significant level and showed moderate variances in pathway signature scores, there was a clear trend that more genes associated with these pathways were highly expressed in one diet group compared to the counterpart.

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49 Although we did not detect a favorable trend in SCFAs following MkD, these results might suggest that MkD shapes the gut ecological niche by altering microbiota composition, leading to concomitant increase in bacterial clades with a symbiotic relationship through their metabolites.

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