Long- and short-term effects of fecal microbiota transplantation on antibiotic resistance genes: results from a randomized placebo-controlled trial.

The trial did not reach its primary endpoint; the numerical decrease in infection rate in the FMT arm did not reach statistical significance. 10 ARG assay After 16S rRNA gene sequencing for the preplanned endpoints of the trial, 226 samples with remaining DNA were used for microfluidic quantitative PCR (MFQPCR) to simultaneously detect and quantify 47 ARGs including those for beta-lactams, quinolones, vancomycin, and carbapenem resistance. 13 The ARG panel is provided in Table 1 .

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