Notably, although there was a reduction in ALP levels following six months of adalimumab therapy, this reduction did not reach statistical significance (SMD = -0.38, CI [-0.84, 0.08], I 2 = 0, p = 0.10).
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Efficacy of Biologics in the Treatment of Primary Sclerosing Cholangitis Associated With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.
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