Integrative high-throughput enhancer surveying and functional verification divulges a YY2-condensed regulatory axis conferring risk for osteoporosis.

Cell Genom · 2024 · PMC10943593 · PMID 38335956

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We further examined cis -expression quantitative trait locus ( cis -eQTL) association from GTEx (V8), 29 and we found that most baaSNPs (65.83%) also had nominally significant cis -eQTL association (p < 0.05) with at least one promoter chromatin interaction gene (254 total) in a consistent direction of allelic activity effect with STARR-seq ( Table S9 ).

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