10 , 11 A nominally significant SNP in AR has been identified in a British population, however this was only associated with early onset FPHL. 11 In addition to the AR locus, another locus which has been identified as strongly associated with MPHL is 20p11, first identified in a Suisse cohort and validated in British, Icelandic and Dutch populations. 12 A later study in a German cohort, with men exhibiting the Norwood‐Hamilton pattern of MPHL, corroborated these results. 9 Building on this were studies in a Chinese 13 and Korean 14 cohorts which also associated 20p11 locus with MPHL.
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The sentences
In MPHL, there is a highly significant association of the androgen receptor (AR) locus (Xq11‐12) with early onset of the trait in a Norwood Hamilton pattern. 9 In FPHL, studies in German and Chinese cohorts have not identified an association of the AR locus with FPHL. 10 , 11 A nominally significant SNP in AR has been identi