Missing data analyses The missing data analysis (Table 3 ) to assess the potential impact of missing outcomes on our estimates also showed that NSAID users had increased odds of the outcomes, with the exception of the outcome of worsening in radiographic KOA severity grade in the worst-case scenario, for which the association did not reach statistical significance (P value 0.027) (Table 3 ).
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Association of long-term use of non-steroidal anti-inflammatory drugs with knee osteoarthritis: a prospective multi-cohort study over 4-to-5 years.
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