Soluble lymphocyte activation gene-3 (sLAG3) and CD4/CD8 ratio dynamics as predictive biomarkers in patients undergoing immune checkpoint blockade for solid malignancies.

Br J Cancer · 2024 · PMC10951205 · PMID 38233492

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a strong trendno p-value reported

3e, f ), while for OS only a strong trend could be observed (p early =0.062, p late = 0.066) towards higher levels in patients who survived longer.

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highly significantno p-value reported

This combined score showed a highly significant predictive potential that transcended the relevance of either of the parameters by themselves (p PFS =0.001, p OS = 0.001).

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