Bonferroni correction was applied to account for the multiple testing, where P ‐value <.005 was regarded as statistically significant and P ‐value <.05 was regarded as nominally significant. 3 RESULTS 3.1 Characteristics of the study participants A total of 113 256 participants were included in the analysis, including 165 EOCRC and 719 EOCRA cases.
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Association between antibiotic use during early life and early-onset colorectal cancer risk overall and according to polygenic risk and FUT2 genotypes.
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