CD81 and CD82 expressing tumor-infiltrating lymphocytes in the NSCLC tumor microenvironment play a crucial role in T-cell activation and cytokine production.

Therefore, we examined the overall expression based on the NMF criteria without specifying T-cell types and found that NMF cluster2, associated with higher TPSs, displayed an increasing trend ( Figure 1I ).

also in 63,971 other papers

We visualized the relationship between each of the 10 subclusters and TPS data through bar plots and dimension plots, which revealed a clear trend of increased number of specific clusters with increase in TPSs and a decreased number of clusters with low TPSs ( Figure 1C , Supplementary Figure 1C ).

also in 19,460 other papers