COVID-19 in non-hospitalised adults caused by either SARS-CoV-2 sub-variants Omicron BA.1, BA.2, BA.4/5 or Delta associates with similar illness duration, symptom severity and viral kinetics, irrespective of vaccination history.

We did detect a trend towards lower Ct and increasing time since last vaccination dose that was significant for BA.1 infection after 3 doses (β = -0.05 (CI -0.10–0.01); P = 0.031) ( Fig 4E ), but this did not reach statistical significance for the other variants (all P > 0.05) ( S3 Table ).

also in 111,027 other papers