In contrast, the infiltration level and predictive role of RSPO1 + fibroblasts in predicting patient prognosis showed a trend opposite to that of POSTN + fibroblasts.
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Single cell deciphering of progression trajectories of the tumor ecosystem in head and neck cancer.
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The sentences
We found an overall trend of elevated Treg infiltration with decreasing Th17, CD4_Tem, and CD8_Tem proportions during HNSCC progression, which indicated the transition from an immune-activated TME to an immune-exhausted TME.