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BET inhibitors drive Natural Killer activation in non-small cell lung cancer via BRD4 and SMAD3.

Nat Commun · 2024 · PMC10960013 · PMID 38519469

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We did not observe a perturbation in the percentage of different immune cell subsets in mouse tumors comparing OTX015- to vehicle-treated mice, with only a trend of increase of tumor-infiltrated NKs that did not reach statistical significance (Fig. 7G, H ).

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