Furthermore, regarding different groups of combinations of exposures and LGA risk, a clear trend of increased risk was observed after adjustment (P trend = 0.0004).
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Pre-pregnancy body mass index, gestational diabetes mellitus, and gestational weight gain: individual and combined effects on fetal growth.
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They also observed an increasing trend of LGA prevalence with increasing GWG across all combinations of GDM and pre-pregnancy BMI categories, indicating an additive effect of GWG, pre-pregnancy BMI, and GDM on LGA risk ( 15 ).